Why aren’t DNA tests 100 per cent accurate?
Upon finding out the genetics tests aren't always 100% accurate the entirety of the chat shows guest list shuddered in relief.
Asked by: Gary Ward, US
Assuming there is enough DNA to read, DNA tests should certainly be able to identify genes – how you differ to other groups of people, say, if it were an ancestry test; or whether you have a gene variant associated with a predisposition to a disease.
But how that is understood, interpreted or used is where things get complicated. Many false-positive and false-negative results can happen because of ‘quirks’ in our chromosomes. You can get different estimates of how recently we share ancestors. And it’s hard to determine the significance of a mutation you may carry.